Hi @parthu-reddy ,
Thanks for the additional information. Thinking about it further, I suspect this was a temporary network outage. It could have been DNS related, or who knows what.
As for your configuration...
5000 is definitely too high; set this towards 100-500 max. If you're working on a load-balanced cluster, this should be done at the load balancer instead.
I was incorrect about api.nuget.org, that is also used by the V3 API. I thought it was only V2. So please disregard.
It's unlikely metadata caching will help, but you could try it. That's a relatively short-lived cache meant for traffic bursts, and it's not really going to help with a network outage.
-- Dean