Hi @paul-kendik_9721 ,
It looks like you're on the right track with troubleshooting -- the issue is indeed related to SSL/Certificates. This is all handled at the operating system level, which means there's nothing we can do on the application (i.e. ProGet) side of things.
Unfortunately, I've never seen this error on a modern Windows server so I don't know what exactly to suggest to fix. I didn't even know TLS 1.0 was enabled on Windows still. Maybe it's not even the server, but like a proxy or some kind of intermediate server?
The "good news" is that this is an easily searchable problem, so I would start by searching for "Windows 2022 SSL HandshakeFailure TLS 1.0" and see what comes up. There is certainly some kind of setting on your server taht is causing this problem, I just don't know what to suggest to look for.
Please let us know wat you find!
Alana